My favorite would-be pairing would have to be Akabane X Ginji from Get Backers... and if you dont know who they are then you should totally read the manga (but avoid the anime... it sucks)
My favorite actual paring is definitely Soubi X Ritsuka from Loveless because Ritsuka is just sooo adorable! and Soubi is like my ideal seme character.
So yeah, those are my favorites... what are yours??
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When LIFE gives you lemons squeeze them in LIFES eyes and make a run for it.